Drug: B12

A Highly Potent Oral Antianemia Preparation Each capsule contains: Special Liver-Stomach Concentrate (containing Intrinsic Factor) 240mg Vitamin B 12 (activity equivalent) 15mcg Iron, Elemental (as Ferrous Fumarate) 110mg Ascorbic Acid (Vitamin C) 75 mg Folic Acid 0.5 mg
    with other factors of Vitamin B Complex present in the Liver-Stomach Concentrate.
Inactive Ingredients: D&C Red #28, FD&C Blue #1, FD&C Red #40, gelatin, magnesium stearate, povidone, silicon dioxide, sodium lauryl sulfate, starch and titanium dioxide.Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.

Source: http://www.rxlist.com

Rarely, iron in therapeutic doses produces gastrointestinal reactions, such as diarrhea or constipation. Reducing the dose and administering it with meals will minimize these effects in the iron-sensitive patient. In extremely rare instances, skin rash suggesting allergy has been noted following the oral administration of liver-stomach material. Allergic sensitization has been reported following both oral and parenteral administration of folic acid.
Read the B12 (liver-stomach concentrate with intrinsic factor) Side Effects Center for a complete guide to possible side effectsLearn More »

Source: http://www.rxlist.com

One capsule twice a day. (Two capsules daily produce a standard response in the average uncomplicated case of pernicious anemia.)

Source: http://www.rxlist.com

No information provided.Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.

Source: http://www.rxlist.com

Hematinic concentrate with intrinsic factor is a multifactor preparation effective in the treatment of anemias that respond to oral hematinics, including pernicious anemia and other megaloblastic anemias and also iron-deficiency anemia. Therapeutic quantities of hematopoietic factors that are known to be important are present in the recommended daily dose.

Source: http://www.rxlist.com

Hemochromatosis and hemosiderosis are contraindications to iron therapy.Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.

Source: http://www.rxlist.com

Symptoms Those of iron intoxication, which may include pallor and cyanosis, vomiting, hematemesis, diarrhea, melena, shock, drowsiness, and coma. Treatment For specific therapy, exchange transfusion and chelating agents. For general management, gastric and rectal lavage with sodium bicarbonate solution or milk, administration of intravenous fluids and electrolytes, and use of oxygen.

Source: http://www.rxlist.com

Capsule, ruby red and opaque scarlet; imprinted E 5380, available in 10 x 10 unit dose packages. Storage Store at controlled room temperature 15°-30°C (59°-86°F). Protect from moisture. Rx only Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.

Source: http://www.rxlist.com

General Anemia is a manifestation that requires appropriate investigation to determine its cause or causes. Folic acid alone is unwarranted in the treatment of proof vitamin B12 (liver-stomach concentrate with intrinsic factor) deficiency states, such as pernicious anemia. Folic acid may obscure pernicious anemia in that the blood picture may revert to normal while neurological manifestations remain progressive. As with all preparations containing intrinsic factor, resistance may develop in some cases of pernicious anemia to the potentiation of absorption of physiologic doses of VITAMIN B12 (liver-stomach concentrate with intrinsic factor) . If resistance occurs, parenteral therapy, or oral therapy with so-called massive doses of VITAMIN B12 (liver-stomach concentrate with intrinsic factor) may be necessary for adequate treatment of the patient. No single regimen fits all cases, and the status of the patient observed in follow-up is the final criterion for adequacy of therapy. Periodic clinical and laboratory studies are considered essential and are recommended. Pregnancy Pregnancy Category C: Animal reproduction studies have not been conducted. It is also not known whether this product can cause fetal harm when administered to a pregnant woman or can effect reproduction capacity. It should be given to a pregnant woman only if clearly needed. Nursing Mothers It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when this product is administered to a nursing woman. Pediatric Use Safety and effectiveness in children below the age of 10 have not been established.Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.

Source: http://www.rxlist.com

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